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Kyle Mathews's avatar

Biology models are just starting to get going too & might be massively valuable.

I think OpenAI is somewhat aware of this too judging by Sam Altman's comments this summer:

> Sam Altman says the perfect AI is “a very tiny model with superhuman reasoning, 1 trillion tokens of context, and access to every tool you can imagine.”

https://www.reddit.com/r/singularity/comments/1l32s24/sam_altman_says_the_perfect_ai_is_a_very_tiny/

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John Neil Conkle's avatar

dovetails with the Josh Wolfe thesis from a recent JPM conference. He pretty much nailed the late October to November price action in public markets.

**Summary: Chase Coleman, Brad Gerstner, Josh Wolfe at Robin Hood 2025**

Here are the key takeaways from the panel discussion on the future of AI and investing:

**The Macro View: The "Layer Cake"**

* **Massive Build-out:** The panel estimates a $3–4 trillion compute build-out over the next 4–5 years (10x the Manhattan Project). Gerstner argues we are only in the early innings of a decade-long shift to accelerated compute. [00:02:08]

* **Where Value Accrues:** Unlike the SaaS boom, the "Layer Cake" theory suggests the semiconductor layer (chips & memory) will capture the most economic rent over the next decade. [00:04:23]

* **Edge vs. Center:** Wolfe argues that 50% of inference will eventually happen on-device (edge) rather than in data centers, which heavily benefits memory players. [00:07:22]

**Stock Picks & Company Views**

* **Nvidia:** Consensus long due to massive scale advantages, despite expected volatility. [00:16:53]

* **OpenAI vs. Anthropic:** The panel favors OpenAI for consumer dominance (zero switching costs, massive adoption). Anthropic is viewed as a likely acquisition target for Amazon, Google, or Meta. [00:10:15]

* **Meta:** Strong bullish sentiment. They are effectively building the "next hardware platform" (glasses/wrist) to bypass Apple/Google and owning the open-source model space. [00:12:07]

* **Top Picks:**

* **Gerstner:** Nvidia and OpenAI.

* **Wolfe:** SK Hynix (High Bandwidth Memory constraints) and Anduril (Defense/Autonomy). [00:14:28]

* **Shorts:** Wolfe calls publicly traded Quantum Computing and Modular Nuclear Reactor stocks "flapdoodle" and potential bubbles. [00:18:26]

**Future Disruptions**

* **The End of "Toll Booths":** The business model of the last 20 years (Google sending traffic to intermediaries like Expedia/Booking) is at risk. AI Agents will execute tasks directly, potentially bypassing the "tax collectors" of the web. [00:21:04]

* **"Fixware":** A rising category focused on maintenance tech (sensors, robotics) to extend the life of physical assets as the cost of capital remains higher. [00:24:39]

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